Intellectual and Developmental Disabilities Grants

The Lawrence Foundation is a private family foundation focused on making grants to support environmental, human services and other causes.

The Lawrence Foundation was established in mid-2000. We make both program and operating grants and do not have any geographical restrictions on our grants. Nonprofit organizations that qualify for public charity status under section 501(c)(3) of the Internal Revenue Code or other similar organizations are eligible for grants from The Lawrence Foundation.  

Grant Amount and Types

Grants typically range between $5,000 - $10,000. In some limited cases we may make larger grants, but that is typically after we have gotten to know your organization over a period of time. We also generally don’t make multi-year grants, although we may fund the same organization on a year by year basis over a period of years.

General operating or program/project grant requests within our areas of interests are accepted. In general, regardless of whether a grant request is for general operating or program/project expenses, all of our grants will be issued as unrestricted grants.

The Foundation is dedicated to providing financial assistance to organizations committed to improving our world. Solutions to the problems of today's world still lie in the values of innovation, practicality, hard work, and compassion.

The Foundation considers applications for grants in the following areas:

• Education
• Social Service
• Health care
• Civic and cultural
• Environmental

The categories above are not intended to limit the interest of the Foundation from considering other worthwhile projects. In general, the Foundation guidelines are broad to give us flexibility in providing grants.

The majority of our grants are made in the U.S. However, like Dr. Scholl, we recognize the need for a global outlook. Non-U.S. grants are given to organizations where directors have knowledge of the grantee.

Philanthropy is our commitment to communities in which we operate and broader society. We focus our resources on a limited number of key projects that can deliver valuable benefits from our contributions and those of our partners. We give priority to innovative, high-quality projects that meet the following criteria:

• promote sustainable development
• offer an opportunity for Roche to use its expertise and logistics capabilities
• involve Roche actively at an early stage with local authorities and established partners
• engage Roche employees in cultural (focus on contemporary arts), educational and social activities
• managed by an accredited charity

Our four focus areas

Humanitarian and Social

We direct the majority of our philanthropic donations to humanitarian and social development projects.

Science and education

We are dedicated to programmes that promote scientific interest and provide educational opportunities for young people around the world.

Community and Environment

We are committed to building stronger communities and responding to natural disasters sustainably.

Arts and Culture

We support groundbreaking contemporary art, cultural projects and activities that explore the parallels between innovation in art and in science. 

Mission

The mission of the Hearst Foundations is to identify and fund outstanding nonprofits to ensure that people of all backgrounds in the United States can build healthy, productive and satisfying lives. Through its grantmaking, the Hearst Foundations support well-established nonprofit organizations that address significant issues within their major areas of focus—culture, education, health and social service—and that primarily serve large demographic and/or geographic constituencies. In each area of funding, the Foundations seek to identify those organizations achieving truly differentiated results relative to other organizations making similar efforts for similar populations. The Foundations also look for evidence of sustainability beyond their support.

Whether providing a scholarship to a deserving student, supporting a rural health clinic or bringing artists into schools so children can see firsthand the beauty of the arts, the Foundations’ focus is consistent: to help those in need, those underserved and those underrepresented in society. Since the Foundations were formed in the 1940s, the scale and capabilities of the grant making have changed, but the mission has not.

Culture Grant

The Hearst Foundations fund cultural institutions that offer meaningful programs in the arts and sciences, prioritizing those that enable engagement by young people and create a lasting and measurable impact. The Foundations also fund select programs nurturing and developing artistic talent. Supported organizations include arts schools, ballets, museums, operas, performing arts centers, symphonies and theaters.

Funding Priorities in Culture

In the recent past, 25% of total funding has been allocated to Culture. Organizations with budgets over $10 million have received 60% of the funding in Culture.

The Hearst Foundations are only able to fund approximately 25% of all grant requests, of which about 80% is directed to prior grantees and about 20% is targeted toward new grantees.

Types of Support

Program, capital and, on a limited basis, general and endowment support

Helping Build Better Futures

Our mission is to deliver great value to our customers every day. For over four decades, our deep commitment to the principles of providing value and caring for others has helped define our culture. It extends beyond the walls of our stores, distribution centers, and offices, and into our local communities around the world. The intersection of these principles defines our global community mission:

Deliver great value to our communities by helping vulnerable families and children access the resources and opportunities they need to build a better future.

Our Social Impact Areas

We bring our community relations mission to life around the world by focusing our giving on four social impact areas where we believe we can have the most impact and are critical to helping families and children succeed and thrive.

Basic Needs

We are passionate about supporting nonprofit organizations that help fill critical basic needs such as a warm meal, clean clothing, and a safe place to sleep for vulnerable families.

Education & Training

Our efforts have focused on quality enrichment and extracurricular programs that provide skills, resources, and opportunities to support school and career success for children, teens, and young adults.

Patient Care & Research

We support organizations that deliver services to families and children facing health challenges and life-threatening illnesses.

Empowering Women

We support programs that provide services ranging from help for those fleeing domestic violence, to others that offer education, training, and job placement resources.

Helping the Disadvantaged Become Self-Reliant

Gupta Family Foundation is a private, nonprofit foundation headquartered in Herndon, Virginia, USA. Our mission is to support organizations that provide focused intervention in the lives of people who have been disadvantaged in some way to help them become self-reliant. We take a very broad view of “disadvantage” to include anything that holds a person back from realizing their potential, such as poverty, physical or mental disability, social alienation, etc. The foundation also supports relief agencies that serve people affected by emergencies such as natural disasters.

The foundation evaluates and awards annual and multi-year grants ranging from $5,000 to over $250,000 (USD). Our focus is on funding smaller organizations all around the world that are led by individuals with a deep personal commitment to their missions. 

Our selection criteria include:

• Mission alignment
• The organization is run by the founder or, if not, by a successor who embodies the original inspiration, passion and commitment of the founder.
• At least 90% of grant monies reaches the intended beneficiaries.
• The organization is non-sectarian, i.e.,
  • It does not, directly or indirectly, support or condone the proselytization of any religion,
  • It is not supported by or affiliated to a religious organization.

Michael & Susan Dell Foundation Grants

The Michael & Susan Dell Foundation only accepts unsolicited proposals for specific areas within the education, family economic stability and childhood health sectors in select countries where we work, namely the United States, India and South Africa.

As a guideline, the foundation does not fund more than 25% of a project’s budget or more than 10% of an organization’s total annual operating expenses.

The Michael & Susan Dell Foundation has always recognized the power of providing grants to partner organizations that we knew were already working hard to improve the lives of urban children living in poverty. By aligning with organizations that are already making a difference, we continue to make an immediate impact on the lives of thousands of children.

Foundation priorities:

We fund social enterprises that directly serve or impact children or youth from urban low-income communities in the areas of education, health, and family economic stability (including livelihoods and financial inclusion). These social enterprises may be structured as for-profit or nonprofit entities.

Partnerships

We collaborate with a range of organizations focused on creating opportunities for children and families living in urban poverty, with a deep emphasis on measuring impact. Our funding advances projects already making an impact in education, health, and family economic stability. Through these enduring and long-standing partnerships, we create lasting change together.

Background

Draper Richards Kaplan Foundation seeks to dramatically improve the lives of underserved communities across the globe by supporting scalable, innovative, and impact-first solutions that leverage existing systems and stakeholders. Our goal is to find social entrepreneurs with dynamic products or services that have a proven ability to positively impact the lives of underserved people, and nurture those organizations at the early stages by providing capacity, capital, and community.

Our application process is designed to be open and accessible, and we accept applications year round from across our priority geographies and sectors. Borrowing from our venture capital legacy, we find exceptional entrepreneurs and provide them with: 

Capacity

• The core of DRK’s model is deep and extensive operational and technical support for each portfolio organization, both through dedicated hands-on Board service and specialist capacity-building resources for fundraising, board and organizational development, leadership, financial support, and scaling strategy,

Capital

• DRK provides up to $300,000 USD in either unrestricted grant funding or investment capital over a three-year period, and

Community

• DRK convenes our portfolio and alumni annually, facilitating connections and community. 

What We Fund

DRK Foundation funds early-stage social impact organizations solving the world’s biggest social and environmental problems using bold, scalable approaches.

What stage of growth does DRK Foundation typically fund?

Early stage: Organizations who are early stage, which we define as post-pilot and pre-scale. This typically means: 

• Your program, product or service is already being used in the market or in the field, 
• You have early indication that your model is having its intended impact on the beneficiary populations,
• Your organization is relatively young (ideally between two and five years old, although we will consider both younger and older organizations).

Venture funding: In the case of for profits, we typically support Seed to Series A organizations, and never lead rounds; we also generally but not exclusively refrain from participating in financings exceeding a $15M USD post-money valuation.  

Mission

The DanPaul Foundation will use its resources to help train teachers and parents in early childhood development, protect children from abuse and neglect, stimulate children's personal social responsibilities, and offer them opportunities for enrichment and growth.

The Foundation will also encourage children to be concerned and informed about the environment and the underprivileged, particularly with regard to clean air and water, and adequate housing and nutrition for all.

Beliefs

The DanPaul Foundation believes that children should have ample opportunities for enrichment in their lives, and thus strives to provide many different ways to enrich and expand children's minds through direct programs and monetary support to organizations doing similar work.

We have provided or currently provide grants related to the following program areas:

• Workshops, Conferences, + Seminars: We strive to offer educational workshops, conferences, and seminars for parents and teachers on topics related to early childhood development.
• Student Scholarships: We aim to help students attending post-secondary education institutions by providing need-based and academic scholarships.
• Scientific Endeavors: We desire to advance scientific endeavors which seek to improve the quality of life for everyone in the world.
• Clean Air + Water: We hope to pass on knowledge and practical life skills to youth regarding their personal responsibility to the environment, teaching them about issues surrounding clean air and water.
• Child Advocacy: We believe in protecting children from abuse and neglect and particularly love to support programs that provide education and assistance to children as well as organizations advocating or caring for vulnerable children.
• Homelessness: We want to encourage young people to take a personal interest in seeing that adequate housing and proper nutrition, especially for the underprivileged and homeless, are available.
• Poverty + Neglect: We seek to help those in poverty as well as educate youth about their responsibility to consider the underprivileged and take care of those most in need of life's basic essentials like adequate housing and proper nutrition.
• Refugee Enrichment: We wish to help refugee youth by supporting programs that provide them enrichment and help them transition to life in a new country.

The DanPaul Foundation provides grants to 501(c)3 tax-exempt non-profit organizations as defined by the IRS. The Foundation is interested in providing funding to programs that directly serve the health, education, development, and welfare of the world's youth.

Grants range from a few hundred dollars up to $15,000 per calendar year.

Mission

To provide financial and other resources to improve the lives of individuals with intellectual and developmental disabilities.

Vision

Our vision is one of lasting progress and sustainable solutions to address the range of needs among the intellectual and developmental disabilities population. We envision a world where these individuals are celebrated for their unique gifts. We want families to have open access to resources and information they need to make decisions about best-in-class care for their loved ones. We imagine a world where local communities are actively engaged in learning from and receiving the meaningful contributions of individuals with intellectual and developmental disabilities by including them in the fabric of the community.

Funding Priorities

The Enterline Foundation’s overarching funding priority is to increase access to services for adults with intellectual and developmental disabilities. Believing that an adequate direct support professional (DSP) workforce is essential to ensuring the provision of services, The Foundation will focus its giving in 2025 on initiatives that support the recruitment and retention of DSPs. Although not limited to these examples, initiatives could include:

• Internship programs
• New hire welcoming, orientation and coaching 
• Training and professional development including certification programs
• Establishment of career ladders
• Connection to community resources for nonwork related needs of DSPs
• Improvements to organizational culture
• Communication and feedback soliciting initiatives
• Recognition and appreciation activities
• Front line supervisor coaching and development
• Technology needed to support data collection and employee experience

Funding Amount

Not to exceed $25,000. One year in duration.

Community Grants

State Farm is committed to helping build safer, stronger and better-educated communities.

• ​​​​​​​​​​​​​​​​We are committed to auto and home safety programs and activities that help people manage the risks of everyday life.
• We invest in education, economic empowerment and community development projects, programs and services that help people realize their dreams.
• We help maintain the vibrancy of our communities by assisting nonprofits that support community revitalization.

Good Neighbor Citizenship company grants focus on safety, community development and education.

Focus Areas

Safety Grants

We strive to keep our customers and communities safe. That's why our funding is directed toward:

• Auto safety — improving driver, passenger, vehicle or roadway safety
• Home safety — shielding homes from fires, crime or natural disasters
• Disaster preparedness and mitigation
• Disaster recovery

Community Development

We support nonprofits that invest and develop stronger neighborhoods. That's why our funding is directed toward:

• Affordable housing — home construction and repair
• Commercial/small business development
• Job training
• Neighborhood revitalization
• Financial literacy
• Sustainable housing and transportation
• Food insecurity

Education

Our education funding is directed toward initiatives that support the following programs:

• Higher education
• K-12 academic performance
• K-12 STEM
• Pathways for college and career success

The Dudley T. Dougherty Foundation Vision

The Dudley T. Dougherty Foundation, "A Foundation for All", was established in 2002. It was begun in order to give a clear voice for those who wish to be a part of the many, worthy, forces for change in our world.

We are a foundation whose purpose is to look ahead towards the future, giving the past its due by remembering where we came from, and how much we can all accomplish together. We aim to make the critical difference on our planet by recognizing and having respect for our ever changing world. We respect all Life, the Environment, and all People, no matter who they are.

Our Mission

The Tony Robbins Foundation is a nonprofit organization created to empower individuals and organizations to make a significant difference in the quality of life of people often forgotten.

We’re dedicated to creating positive changes in the lives of youth, seniors, the hungry, homeless and the imprisoned population, all who need a boost envisioning a happier and deeply satisfying way of life. Our passionate staff, generous donors and caring group of international volunteers provide the vision, inspiration, and resources needed to empower these important members of our society.

Grants

Dedicated to meeting challenges within the global community, creating solutions and taking action, The Tony Robbins Foundation provides monetary donations to various organizations around the world. Funding requests are evaluated on an ongoing basis. We look for organizations that align with our mission to empower individuals and organizations to make a significant difference in the quality of life of those often forgotten.

Background

Governmental public health (GPH) is a fundamental system for protecting and improving population health in all communities. This system works toward preventing and eliminating health inequities while responding and meeting emergency and emergent needs. Transforming governmental health to address structural barriers to health and advancing an equitable system where governmental public health and communities work in collaboration and share power fosters health equity and helps communities thrive. Non-governmental organizations, power-building organizations, and public health professionals are crucial components to this transformation by supporting the priorities, meeting the needs, and holding public health accountable to communities they serve while protecting the integrity and historic health justice orientation of the governmental public health system. The connected systems of both public health and healthcare systems have often failed to provide adequate consideration for the needs of adults with developmental disabilities, resulting in many experiencing these systems as a source of harm and mistrust. These systems can have a disparate impact on populations that have experienced systems of oppression, including ableism1. Society has traditionally looked at disability through a medical model of inability and dependence. These structural barriers are further intensified for individuals experiencing multiple systems of oppression, as racism and ableism1 mutually reinforce each other. There are medical professionals and disability advocates who are actively involved in and leading change toward more equitable public health and healthcare systems. WITH Foundation (WITH) promotes comprehensive healthcare for adults with developmental disabilities in the United States that is designed to address their unique and fundamental needs. WITH embraces an intersectional approach, centers the expertise and leadership of those most impacted by this injustice, is committed to cultural humility5 and addressing power imbalances, and values innovation. In alignment, the Robert Wood Johnson Foundation (RWJF) is a leading national philanthropy dedicated to taking bold leaps to transform health in our lifetime. To get there, we must work to dismantle structural racism and other barriers to health. Through funding, convening, advocacy, and evidence-building, RWJF works side-by-side with communities, practitioners, and institutions to achieve health equity faster and pave the way, together, to a future where health is no longer a privilege, but a right.

RFP Advancing Disability Justice in Public Health—New Funding Opportunity

This is an invitation for collaborative proposals that advance disability justice6 in public health and center the goals, perspectives, and needs of adults with intellectual and developmental disabilities (I/DD) in Communities of Color. The efforts supported through this RFP will contribute to a public health system that is fair and just, treats all people with dignity and respect, and rectifies past harms and prevents future ones. Proposals should prioritize one of the following approaches:

Implementation: Support implementation of models, i.e., testing and advancing solutions to enhance governmental public health in being trustworthy, accountable, truly collaborative, and anti-racist. Models should support the leadership of and power sharing with adults with intellectual and Developmental Disabilities in Communities of Color, or those with a demonstrated track record of working with Adults with I/DD in Communities of Color;

Educational resources: Developing public health curriculum and/or training resources with Adults with Intellectual and Developmental Disabilities in Communities of Color, and/or creating/leveraging networks supporting resource dissemination and utilization within public health and disability justice6 ecosystems, helping public health systems become more accountable to Adults with Intellectual and Developmental Disabilities in Communities of Color – communities that have been historically marginalized.

Advocacy, Power and Bridging: Support regional or national advocacy, community power building to build and shift power, and bridging between governmental public health with entities such as grassroots organizing groups, social movement groups, movement-building organizations, community-based organizations, community organizing groups, and base-building groups related to the care that Adults with Intellectual and Developmental Disabilities in Communities of Color receive within public health; and

Research: Identify and close gaps in knowledge and inform efforts to improve health related to the care Adults with Intellectual and Developmental Disabilities in Communities of Color receive, i.e., community-based or community-led research that assists disability-led organizations in illuminating and addressing structural barriers within the governmental health system that are experienced by Adults with Intellectual and Developmental Disabilities in Communities of Color.

Community Partnership Award

The Mutual of America Foundation Community Partnership Award recognizes outstanding nonprofit organizations in the United States that have shown exemplary leadership by facilitating partnerships with public, private or social sector leaders who are working together as equal partners, not as donors and recipients, to build a cohesive community that serves as a model for collaborating with others for the greater good.

Each year, the Mutual of America Foundation sponsors a national competition in which hundreds of organizations demonstrate the value of their partnership to the communities they serve, their ability to be replicated by others and their capacity to stimulate new approaches to addressing significant social issues.

Six organizations are selected by an independent committee to receive the Community Partnership Award.

• The Thomas J. Moran Award is given to the national award-winning program and includes $100,000 and a documentary video about the program.
• The Frances R. Hesselbein Award is given to a partnership that is addressing social challenges in more than one community, or which demonstrates the potential to be replicated in other communities. This recipient receives $75,000.
• Four other organizations are named Honorable Mention recipients for their programs, and each receives $50,000.

Since its inception in 1996, the Community Partnership Award has recognized 262 partnerships from cities and towns across America. Like so many of our clients working in the nonprofit community, Mutual of America is dedicated to having a direct, positive impact on society.

We have strong partnerships with nonprofit organizations across the country that are working to advance economic mobility and social progress in low- and moderate-income communities. Our focus areas include basic needs like food and housing, workforce development and education, and community development. In addition to our philanthropic investments, we also encourage our employees to make a difference by offering robust employee giving and volunteering programs, including the opportunity to direct funds to organizations they support through volunteer efforts, and a matching gifts program that doubles their individual giving to causes they care about. Last year, we invested $350 million in the communities we serve, and employees contributed more than 1 million volunteer hours and directed $65 million through individual giving and matching gifts to support nonprofits.Through our regional U.S. sponsorships, we support the economic, social and cultural life of the places we live and work. We provide an extensive program of arts and sports sponsorships to help maintain vibrant, healthy communities.Sponsorships supporting communitiesBank of America welcomes your sponsorship proposal for opportunities that make our communities a better place to live and work. We are particularly interested in providing support to address needs vital to the health of our communities through a focus on:

• preserving neighborhoods;
• educating the workforce for 21st century jobs;
• addressing critical needs such as hunger and emergency shelter;
• arts and culture;
• the environment; and
• diversity and inclusion programs.

Grants are made at the Foundation’s discretion based on our current funding strategies focused on housing, jobs and hunger. 

About Us

The Patient-Centered Outcomes Research Institute (PCORI) is an independent, nonprofit research organization that seeks to empower patients and others with actionable information about their health and healthcare choices. We fund comparative clinical effectiveness research (CER), which compares two or more medical treatments, services, or health practices to help patients and other stakeholders make better informed decisions.

Since its authorization by Congress in 2010, PCORI has awarded more than $3 billion to fund nearly 2,000 research and related projects (explore our research portfolio). PCORI-funded research studies produce important results that are published in leading medical journals and presented at major scientific meetings. Results from studies we have funded are also taken up in a variety of clinical guidelines. We post results from every study we fund, with versions for both patients and clinicians. 

In 2019, PCORI’s funding was reauthorized, with additional research priorities—intellectual and developmental disabilities and maternal morbidity and mortality—and a mandate to consider, as appropriate, the full range of outcomes data, including the potential burdens and economic impacts of the use of medical treatments, items, and services for different stakeholders in the research we fund.

PCORI is committed to transparency and a rigorous stakeholder-driven process that emphasizes patient engagement. PCORI uses a variety of forums and public comment periods to obtain public input to enhance its work. PCORI helps people make informed healthcare decisions and improves healthcare delivery and outcomes by producing and promoting high-integrity, evidence-based information that comes from research guided by patients and other stakeholders.

The Jordan Spieth Family Foundation focuses on impactful and direct lines of support through our four mission pillars: Individuals with Special Needs, Junior Golf, Military Families and Veterans and Pediatric Cancer. All grant applicants' primary work must fall very specifically within one or more of these areas. For each initiative we support, JSFF seeks to fund achievable ideas that aim to help remove barriers and/or provide opportunities that directly impact individuals and families within our mission focus. Ideally the primary work of each grant should take place within the 2025 calendar year. 

Individuals with Special Needs

The Foundation seeks to partner with programs that close the gap for those with cognitive or neurological special needs, ensuring these children and young adults have access to developmental programming and vocational opportunities to expand their communication, self-help, and social skills. We focus on pursuing partners that create developmental opportunities and promote inclusion for the intellectually disabled.

Junior Golf

We believe the game of golf can be a conduit for many life skills and an on-ramp for expanding youth horizons. The Foundation will focus on junior golf programs that are diverse, emphasize outreach and remove potential socio-economic barriers to the game. We also pursue partnerships with groups that utilize golf as an avenue to furthering education and/or mentorship opportunities.

Military Families and Veterans

In an effort to honor those military members who have served our country, the Foundation pursues established grant partners who directly impact service members and/or their families through financial aid opportunities, familial respite support, mental and physical therapies and avenues that look to provide long-term support mechanisms.

Pediatric Cancer

Our goal is to fund programs that offer direct care for children fighting cancer and their families. This includes supporting child life services, emotional and social therapies, familial respite, and avenues to overcome financial burdens on families when facing a diagnosis. Additionally, the ultimate goal of the JSFF and our partners would be to eradicate pediatric cancers, and we welcome grant applications for research and clinical trials.

Please see FAQs for additional guidelines.

Project CASK Grant Program

Project CASK, in collaboration with the Orphan Disease Center, is seeking proposals to advance research that supports therapeutic development for CASK gene disorders.

Background

The X-linked CASK gene provides instructions for making a protein called calcium/calmodulin-dependent serine protein kinase (CASK), which is primarily found in neurons and helps control the expression of other genes involved in brain development. Mutations on the CASK gene are currently associated with two disorders, microcephaly with pontine and cerebellar hypoplasia (MICPCH) and XL-ID with or without nystagmus. The spectrum of neurological phenotypes associated with CASK variants is broad and includes global developmental delays, intellectual disability, epilepsy, or other seizure disorders, hypotonia, swallowing or feeding challenges, hearing and vision issues, and other neurological symptoms. 

Funding

Proposed funding period is one or two years, beginning about one month after full applications are received.  

The Engagement Award Program is now accepting Letters of Intent (LOIs) for the Engagement Award: Capacity Building funding opportunity. This opportunity aims to build the capacity and skills of patients and stakeholders to engage in all phases of patient-centered comparative clinical effectiveness research (CER).

Award

You may propose projects that will last up to two years and cost up to $300,000.

Notice of Upcoming PCORI Funding Announcement

This PCORI Funding Announcement (PFA) invites applications for high-quality comparative clinical effectiveness research (CER) projects.

All applications must align the proposed research with at least one of the National Priorities for Health described within the PFA (Increase Evidence for Existing Interventions and Emerging Innovations in Health; Accelerate Progress Toward an Integrated Learning Health System; Achieve Health Equity; or Advance the Science of Dissemination, Implementation and Health Communication). Topic Themes are also included in this funding opportunity. Applicants have the option to choose up to three Topic Themes based on how their proposed research aligns with the themes. However, aligning with a Topic Theme is not required. The National Priorities for Health and Topic Themes will assist PCORI in determining the optimal review pathway for the proposed research.

National Priorities for Health

Our National Priorities for Health are a comprehensive set of mutually reinforcing goals that focus on impact and drive research funding and other initiatives to improve patient care and health outcomes. The breadth of the goals allows for flexibility, agility, and responsiveness to both foreseen and unforeseen changes in the healthcare landscape. Although each priority is important on its own, taken together they will allow PCORI to leverage our work, and strengthen relationships with patients and stakeholders, to address the health and healthcare challenges facing the nation today and in the years ahead. Learn more about the National Priorities for Health here.

Funds and Project Period

• Funds available up to approximately $120 million total for all categories (1, 2 and 3)
• Total direct costs:
  • Category 1: Less than or equal to $5 million in direct costs
  • Category 2: Greater than $5 million; up to $12 million in direct costs
  • Category 3: Up to $12 million in direct costs
• Maximum project period up to five years for all categories (1, 2 and 3)

People With Disabilities Foundation Grants

In February 2017, PWDF announced a pilot grant program to help other nonprofit agencies in their work to integrate people with psychiatric, intellectual, and/or developmental disabilities (P/IDD) into the whole of society. Grants may be used for a specific program, project, or general operating expenses if related to a specific project or program in furtherance of providing advocacy, education, vocational, or other services to people with psychiatric and/or developmental disabilities.

PWDF’s Grant Program is accepting LOIs for new grant awards. LOIs must be submitted on PWDF’s LOI form and received by November 6, 2024, to be considered for the next grant cycle. The date of approval will depend on the date of the next Board meeting at which grants are reviewed. 

Rapid advances in genotyping and next generation sequencing technologies have led to the identification of genetic variants that are associated with a wide variety of congenital defects including human congenital anomalies (HCAs), intellectual developmental disabilities (IDDs) and inborn errors of metabolism (IEMs). Large quantities of genomic data collected from pediatric congenital anomalies cohorts are available to the research community through several databases such as the Database of Genotypes and Phenotypes (dbGaP), the Gabriella Miller Kids First Data Resource Portal, the European Genome-Phenome Archive and Clinical Genome Resource (ClinGen). The purpose of this initiative is to promote the screening, functional validation and characterization of congenital anomaly-associated genetic variants identified through public facing databases and individual efforts using in-silico tools, appropriate animal models, in vitro systems or multi-pronged approaches. This initiative addresses a challenging gap between identifying sequence variations of potential interest and recognizing which of those variations have functional effects on the phenotype of interest.